Valsartan Oral Route Proper Use

AUC and C values of valsartan increase linearly and are almost proportional with increasing dose from 40 to 160 mg twice a day. Diovan can cause fetal harm when administered to a pregnant woman. Use of drugs that act on the reninangiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Most epidemiologic studies examining fetal abnormalities after exposure to antihypertensive https://diovan.live/ use in the first trimester have not distinguished drugs affecting the reninangiotensin system from other antihypertensive agents. Published reports include cases of anhydramnios and oligohydramnios in pregnant women treated with valsartan . The largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of stroke, but reductions in myocardial infarction and cardiovascular mortality also have been seen regularly.